diff --git a/srcpkgs/python3-pyside2/patches/crossbuild-for-shiboken2.patch b/srcpkgs/python3-pyside2/patches/crossbuild-for-shiboken2.patch
new file mode 100644
index 00000000000..5a071a33d20
--- /dev/null
+++ b/srcpkgs/python3-pyside2/patches/crossbuild-for-shiboken2.patch
@@ -0,0 +1,11 @@
+--- sources/pyside2/cmake/Macros/PySideModules.cmake.ORIG
++++ sources/pyside2/cmake/Macros/PySideModules.cmake
+@@ -123,7 +123,7 @@
+                         BYPRODUCTS ${${module_SOURCES}}
+                         COMMAND Shiboken2::shiboken2 ${GENERATOR_EXTRA_FLAGS}
+                         "${pyside2_BINARY_DIR}/${module_NAME}_global.h"
+-                        --include-paths=${shiboken_include_dirs}
++                        --include-paths=${shiboken_include_dirs}${PATH_SEP}${CMAKE_FIND_ROOT_PATH}/usr/include
+                         ${shiboken_framework_include_dirs_option}
+                         --typesystem-paths=${pyside_binary_dir}${PATH_SEP}${pyside2_SOURCE_DIR}${PATH_SEP}${${module_TYPESYSTEM_PATH}}
+                         --output-directory=${CMAKE_CURRENT_BINARY_DIR}
diff --git a/srcpkgs/python3-pyside2/patches/crossbuild-no-pyi-generation.patch b/srcpkgs/python3-pyside2/patches/crossbuild-no-pyi-generation.patch
new file mode 100644
index 00000000000..b43838964b5
--- /dev/null
+++ b/srcpkgs/python3-pyside2/patches/crossbuild-no-pyi-generation.patch
@@ -0,0 +1,31 @@
+pyside2 cmake code does not handle crossbuild while generating pyi files.
+(stub files for type checker).
+From now, disable their generation.
+
+--- sources/pyside2/cmake/Macros/PySideModules.cmake.ORIG
++++ sources/pyside2/cmake/Macros/PySideModules.cmake
+@@ -201,18 +201,24 @@
+     endif()
+ 
+     # Add target to generate pyi file, which depends on the module target.
++    if(NOT CMAKE_CROSSCOMPILING)
+     add_custom_target("${module_NAME}_pyi" ALL
+                       COMMAND ${CMAKE_COMMAND} -E env ${ld_prefix}
+                       "${SHIBOKEN_PYTHON_INTERPRETER}"
+                       "${CMAKE_CURRENT_SOURCE_DIR}/../support/generate_pyi.py" ${generate_pyi_options})
+     add_dependencies("${module_NAME}_pyi" ${module_NAME})
++    else()
++      message(STATUS "crossbuild: disable generation of ${module_NAME}_pyi")
++    endif()
+ 
+     # install
+     install(TARGETS ${module_NAME} LIBRARY DESTINATION "${PYTHON_SITE_PACKAGES}/PySide2")
+ 
++    if(NOT CMAKE_CROSSCOMPILING)
+     file(GLOB hinting_stub_files RELATIVE "${CMAKE_CURRENT_BINARY_DIR}/PySide2" "${CMAKE_CURRENT_BINARY_DIR}/PySide2/*.pyi")
+     install(FILES ${hinting_stub_files}
+             DESTINATION "${PYTHON_SITE_PACKAGES}/PySide2")
++    endif()
+ 
+     install(FILES ${CMAKE_CURRENT_BINARY_DIR}/PySide2/${module_NAME}/pyside2_${lower_module_name}_python.h
+             DESTINATION include/PySide2${pyside2_SUFFIX}/${module_NAME}/)
diff --git a/srcpkgs/python3-pyside2/template b/srcpkgs/python3-pyside2/template
index 20253c69c96..3538d3a7998 100644
--- a/srcpkgs/python3-pyside2/template
+++ b/srcpkgs/python3-pyside2/template
@@ -1,26 +1,34 @@
 # Template file for 'python3-pyside2'
 pkgname=python3-pyside2
-version=5.14.1
+version=5.14.2.1
 revision=1
 _pkgname="pyside-setup-opensource-src-${version}"
-wrksrc="$_pkgname"
-configure_args="-DCMAKE_INSTALL_PREFIX=/usr -DCMAKE_BUILD_TYPE=Release
- -DBUILD_TESTS=OFF -DPYTHON_EXECUTABLE=/usr/bin/python"
-hostmakedepends="cmake"
+wrksrc="${_pkgname/%5.14.2.1/5.14.2}"
+build_wrksrc="sources/pyside2"
+build_style=cmake
+configure_args="-DBUILD_TESTS=OFF -DPYTHON_EXECUTABLE=/usr/bin/python"
+hostmakedepends="cmake python3 shiboken2"
 makedepends="python3-devel libshiboken2-devel qt5-devel
  qt5-multimedia-devel qt5-tools-devel qt5-plugin-mysql qt5-plugin-odbc
  qt5-plugin-pgsql qt5-plugin-sqlite qt5-plugin-tds qt5-x11extras-devel
  qt5-xmlpatterns-devel qt5-location-devel qt5-declarative-devel qt5-scxml-devel
  qt5-script-devel qt5-sensors-devel qt5-speech-devel qt5-charts-devel
  qt5-svg-devel qt5-datavis3d-devel qt5-webchannel-devel qt5-websockets-devel
- qt5-3d-devel qt5-gamepad-devel qt5-remoteobjects-devel"
+ qt5-3d-devel qt5-gamepad-devel qt5-remoteobjects-devel
+ $(vopt_if webengine 'qt5-webengine-devel')"
 depends="python3-shiboken2"
 short_desc="Python3 bindings for the Qt5 toolkit"
 maintainer="yopito <pierre.bourgin@free.fr>"
 license="LGPL-3.0-or-later"
 homepage="https://wiki.qt.io/Qt_for_Python"
 distfiles="https://download.qt.io/official_releases/QtForPython/pyside2/PySide2-${version}-src/${_pkgname}.tar.xz"
-checksum=41ce931695567639c92acb68a9d66ed5609f067011af9a94b53fc0d697ad1d1c
+checksum=11f48956208a487dabf6f531e60fb88ad0e48f2979cfc9e79c1c986387c491fa
+
+export CLANG_INSTALL_DIR=${XBPS_CROSS_BASE}/usr
+
+if [ ${CROSS_BUILD} ]; then
+	hostmakedepends+=" qt5-qmake qt5-host-tools qt5-tools qt5-remoteobjects qt5-scxml"
+fi
 
 build_options="webengine"
 desc_option_webengine="Build Qt5 WebEngine bindings"
@@ -29,10 +37,6 @@ if [ "$XBPS_TARGET_ENDIAN" = "le" ]; then
 	build_options_default="webengine"
 fi
 
-if [ "$build_option_webengine" ]; then
-	makedepends+=" qt5-webengine-devel"
-fi
-
 subpackages="libpyside2-python3-devel libpyside2-python3 libpyside-python3
  python3-pyside python3-pyside-phonon python3-pyenet"
 
@@ -40,19 +44,6 @@ if [ "$build_option_webengine" ]; then
 	subpackages+=" python3-pyside2-webengine"
 fi
 
-do_build() {
-	[ ! -d build ] && mkdir build
-	pushd build
-	export CLANG_INSTALL_DIR=/usr
-	cmake ../sources/pyside2 ${configure_args}
-	make ${makejobs}
-	popd
-}
-
-do_install() {
-	make -C build DESTDIR=${DESTDIR} install
-}
-
 python3-pyside2-webengine_package() {
 	depends="python3-pyside2-${version}_${revision}"
 	short_desc+=" - WebEngine component"